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You are here:Home » Antibodies » Abs to Receptors » Anti -AVPR1B (Vasopressin V1b Receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic Hormone Receptor 1b, Vasopressin V3 Receptor, AVPR3, VPR3)

Anti -AVPR1B (Vasopressin V1b Receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic Hormone
Receptor 1b, Vasopressin V3 Receptor, AVPR3, VPR3)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B IH
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. AVPR1B expression has been documented in the pituitary, pituitary tumors, pheochromocytoma, breast cancer, and small-cell lung carcinomas.
Catalog #A3550-08F
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.05-0.2ug/ml
Immunohistochemistry (paraffin): 5-10ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Amygdala lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-PRDLELADGEGTAE, from the C-Terminus of the protein sequence according to NP_000698.1.
SpecificityRecognizes human AVPR1B.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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