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You are here:Home » Antibodies » Abs to Translation Initiation Factors » Anti -Argonaute 1, 2, 3, 4 (Eukaryotic Translation Initiation Factor 2C 1, 2, 3, 4)

Anti -Argonaute 1, 2, 3, 4 (Eukaryotic Translation Initiation Factor 2C 1, 2, 3, 4)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E
Small interfering RNAs (siRNAs) have gained much attention for their powerful ability to suppress gene expression. Introduction of double-stranded RNA (dsRNA), that are homologues in sequence to a gene, has proven to suppress that gene's expression through a process known as RNA interference (RNAi); this process post-transcriptionally silences a gene through mRNA inhibition or degradation. Both biochemical and genetic studies have led to the identification of two, conserved gene families that are universal components of the interference process. These are the Dicer family, which is comprised of members of the Ribonuclease III family of enzymes, and the Argonaute gene family. Argonaute proteins addition to their role in RNAi process, may also influence development, such as, stem cell fate determination.
Catalog #A3570-21
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.025% sodium azide, 50% glycerol.
PuritySerum.
ImmunogenSynthetic peptide corresponding to aa361-378 (TSTMIRATARSAPDRQEE) of human Argonaut 2. (Genbank accession number: NP_036286).
SpecificityRecognizes human Argonaut 2, Argonaut 3 and Argonaut 4. Sequence Homology
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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