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You are here:Home » Antibodies » Abs to Translation Initiation Factors » Anti -Argonaute 2, 3, 4 (Eukaryotic Translation Initiation Factor 2C 2,3,4)

Anti -Argonaute 2, 3, 4 (Eukaryotic Translation Initiation Factor 2C 2,3,4)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit E
Small interfering RNAs (siRNAs) have gained much attention for their powerful ability to suppress gene expression. Introduction of double-stranded RNA (dsRNA), that are homologues in sequence to a gene, has proven to suppress that gene's expression through a process known as RNA interference (RNAi); this process post-transcriptionally silences a gene through mRNA inhibition or degradation. Both biochemical and genetic studies have led to the identification of two, conserved gene families that are universal components of the interference process. These are the Dicer family, which is comprised of members of the Ribonuclease III family of enzymes, and the Argonaute gene family. Argonaute proteins addition to their role in RNAi process, may also influence development, such as, stem cell fate determination.
Catalog #A3570-21A
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
ConcentrationNot determined
FormRabbit sera with 50% glycerol and 0.025% sodium azide
PurityWhole antisera
SpecificitySpecies Crossreactivity: Human
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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