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You are here:Home » Antibodies » Abs to Translation Initiation Factors » Anti -Argonaute 2, 3, 4 (Eukaryotic Translation Initiation Factor 2C 2, 3, 4)

Anti -Argonaute 2, 3, 4 (Eukaryotic Translation Initiation Factor 2C 2, 3, 4)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E
Argonaut 2,3,4, also known as Eukaryotic translation initiation factor 2C, is a member of the Argonaut family of proteins with 861aa. It is a highly basic protein with PAZ and PIWI domains and is well known for its role in short-interfering-RNA-mediated gene silencing (TGS pathway) and RNA interference. It shows identity with rabbit translation initiation factor Eif2c and is necessary for maintaining non-CpG DNA and histone methylation, developmental control, stem cell maintenance, and tumorigenesis. Reports suggest that Argonaut 2,3,4 may be a component of a hypothetical meristem forming competence factor. RT-PCR and ELISA revealed intermediate and nearly uniform levels of expression in all tissues.
Catalog #A3570-21B
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.025% sodium azide, 50% glycerol.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa260-273 LGADVTHPPAGDGK of human Argonaut 2,3,4.
SpecificityRecognizes human Argonaut 2,3,4. Species Crossreactivity: chicken, chimpanzee, bovine, canine, equine, mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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