Anti -Argonaute 2, 3, 4 (Eukaryotic Translation Initiation Factor 2C 2, 3, 4)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
E |
|
| Argonaut 2,3,4, also known as Eukaryotic translation initiation factor 2C, is a member of the Argonaut family of proteins with 861aa. It is a highly basic protein with PAZ and PIWI domains and is well known for its role in short-interfering-RNA-mediated gene silencing (TGS pathway) and RNA interference. It shows identity with rabbit translation initiation factor Eif2c and is necessary for maintaining non-CpG DNA and histone methylation, developmental control, stem cell maintenance, and tumorigenesis. Reports suggest that Argonaut 2,3,4 may be a component of a hypothetical meristem forming competence factor. RT-PCR and ELISA revealed intermediate and nearly uniform levels of expression in all tissues. | | | Catalog # | A3570-21C | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | ELISA: 1:100-1:1000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not determined. | | Form | Supplied as a liquid, 0.025% sodium azide, 50% glycerol. | | Purity | Serum | | Immunogen | Synthetic peptide corresponding to aa132-148 HLKSFTEQLRKISRDAG of human Argonaut 2,3,4. | | Specificity | Recognizes human Argonaut 2,3,4. Species Crossreactivity | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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