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ARL2BP, Recombinant, Human (ADP-ribosylation Factor-like 2 Binding Protein, ARF-like 2-binding Protein, Binder of ARF2 Protein 1, BART, BART1)
ARL2BP, Recombinant, Human (ADP-ribosylation Factor-like 2 Binding Protein, ARF-like
2-binding Protein, Binder of ARF2 Protein 1, BART, BART1)
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| ARL2BP is an effector of ADP-ribosylation factor-like 2(ARL2) that is essential for nuclear retention of STAT3. This protein binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. Though predominantly cytosolic, ARL2BP can enter the mitochondria and bind the adenine nucleotide transporter when bound to ARL2. Thus it may also be involved in mitochondria transport and apoptosis. | | | Catalog # | A3570-84Q | | Source | Recombinant corresponding to aa1-163 of human ARL2BP protein, fused to His-tag at N-terminus, expressed in E.coli. | | AA Sequence | MGSSHHHHHH SSGLVPRGSH MDALEGESFA LSFSSASDAE FDAVVGYLED IIMDDEFQLL QRNFMDKYYL EFEDTEENKL IYTPIFNEYI SLVEKYIEEQ LLQRIPEFNM AAFTTTLQHH KDEVAGDIFD MLLTFTDFLA FKEMFLDYRA EKEGRGLDLS SGLVVTSLCK SSSLPASQNN LRH | | Molecular Weight | 20.9kD (183aa) confirmed by MALDI-TOF | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 20.9kD | | Source | E.coli | | Purity | ~90% (SDS-PAGE). | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 20mM Tris-HCl, pH 7.5, 10% Glycerol. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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