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ARL3, Recombinant, Human, aa1-182, His-tag (ADP-ribosylation Factor-like Protein 3, ARFL3)
ARL3, Recombinant, Human, aa1-182, His-tag (ADP-ribosylation Factor-like Protein 3, ARFL3)
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| ARL3, is a member of the ARF-like protein (ARL) subfamily of small GTPases. Unlike ARFs, ARL3 does not activate the cholera toxin ADP-ribosyltranferase. This protein is ubiquitously expressed. It may play a role in maintaining rod photoreceptor cells and regulating microtubule-dependent processes. Knockdown of ARL3 leads to altered cell morphology, failure of cytokinesis, acetylation of alpha tubulin and an increase in binucleated cells. | | | Catalog # | A3570-85M | | Source | Recombinant corresponding to aa1-182 from human ARL3, fused to His-tag at N-terminal expressed in E.coli. | | AA Sequence | MGSSHHHHHH SSGLVPRGSH MGSHMGLLSI LRKLKSAPDQ EVRILLLGLD NAGKTTLLKQ LASEDISHIT PTQGFNIKSV QSQGFKLNVW DIGGQRKIRP YWKNYFENTD ILIYVIDSAD RKRFEETGQE LAELLEEEKL SCVPVLIFAN KQDLLTAAPA SEIAEGLNLH TIRDRVWQIQ SCSALTGEGV QDGMNWVCKN VNAKKK | | Molecular Weight | ~23kD (MALDI-TOF) | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | ~23kD | | Source | E.coli | | Purity | ~95% (SDS-PAGE) | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 30% glycerol, 0.1M sodium chloride, 1mM DTT, 0.1mM PMSF. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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