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ARL11, Recombinant, Human aa1-196, His-tag (ADP-ribosylation factor-like 11, ARLTS1)
ARL11, Recombinant, Human aa1-196, His-tag (ADP-ribosylation factor-like 11, ARLTS1)
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| ARL11(ADP-ribosylation factor-like protein 11), is a member of the ARF family of the Ras superfamily of small GTPases that are known to be involved in multiple regulatory pathways altered in human carcinogenesis. ARFs are highly conserved guanine nucleotide binding proteins that enhance the ADP-ribosyltransferase activity of choleratoxin. ARFs are important in eukaryotic vesicular trafficking pathways and they play an essential role in the activation of phospholipase D (PC-PLD). ARL11 is thought to function as a tumor suppressor that may play a role in the regulation of apoptosis. Purified by using conventional chromatography techniques. | | | Catalog # | A3570-99 | | Source | Recombinant corresponding to aa1-196 of human ARL11, fused to His-tag at N-terminal, expressed in E.coli. | | AA Sequence | MGSSHHHHHH SSGLVPRGSH MGSVNSRGHK AEAQVVMMGL DSAGKTTLLY KLKGHQLVET LPTVGFNVEP LKAPGHVSLT LWDVGGQAPL RASWKDYLEG TDILVYVLDS TDEARLPESA AELTEVLNDP NMAGVPFLVL ANKQEAPDAL PLLKIRNRLS LERFQDHCWE LRGCSALTGE | | GLPEALQSLW SLLKSRSCMC LQARAHGAER GDSKRS | | Molecular Weight | ~23.6kD (216aa), confirmed by MALDI-TOF | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | ~23.6kD | | Source | E.coli | | Purity | ~90% (SDS-PAGE) | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in 20mM Tris-HCl buffer, pH 8, 5mM DTT, 100mM sodium chloride, 1mM EDTA, 30% glycerol. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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