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You are here:Home » Antibodies » Abs to GTPase, Rab, Ras, Rho Proteins » Anti -ARMER, CT (ADP-ribosylation Factor-like Protein 6-interacting Protein 1, ARL-6-interacting Protein 1, AIP1, Aip-1, ARL6IP1, ARL6IP, KIAA0069)

Anti -ARMER, CT (ADP-ribosylation Factor-like Protein 6-interacting Protein 1,
ARL-6-interacting Protein 1, AIP1, Aip-1, ARL6IP1, ARL6IP, KIAA0069)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified B IH
Apoptosis is important for normal development and tissue homeostasis. It is mediated by various caspases andultimately results in the activation of endogenous endonucleases that degrade cellular DNA. Although apoptosis induced by endoplasmic reticulum (ER) stress is thought to be mediated by caspase-12, other caspases such as caspase-9 are also thought to be activated following ER stress. Recently, ARMER, a novel integral ER-membrane protein was shown to protect cells from ER stress-induced apoptosis. Analysis of the caspase proteolytic cascade suggests that ARMER acts by inhibiting caspase-9 activity, although the mechanism for this remains unkown. It should be noted that ARMER is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.
Catalog #A3571-05D
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-2ug/ml
Immunohistochemistry (paraffin): 2ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman bladder cell lysates.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified
ImmunogenSynthetic peptide corresponding to human ARMER.
SpecificityRecognizes human ARMER. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesADP-ribosylation Factor-like 6 Interacting Protein 1


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