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Specifications

Clone Host Grade Applications Polyclonal Rabbit Highly Purified B IH

ARMER is an integral ER-membrane protein involved in protein transport, membrane trafficking and cell signalling. ARMER has been shown to protect cells against ER stress-induced apoptosis, possibly by blocking caspase-9 activity. It is expressed in all haematopoietic cell lineages with highest expression in early myeloid progenitor cells. It is expressed in brain, bone marrow, thymus and lung with lower levels in liver, kidney and spleen. It is not detected in heart.
Catalog #	A3571-05E
Applications	Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended Dilution	Western Blot: 0.5-2ug/ml
	Immunohistochemistry (Paraffin): 2ug/ml
	Optimal dilutions to be determined by the researcher.
Immunohistochemistry Positive Control Tissue	Human bladder
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgG
Host	Rabbit
Source	Human
Concentration	As reported
Form	Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
Purity	Purified by Ion Exchange chromatography.
Immunogen	Synthetic peptide corresponding to 15aa near the carboxy terminus of human ARMER.
Specificity	Recognizes the CT ARMER in human bladder cell lysates at ~27kD. Species crossreactivity: mouse.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.