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You are here:Home » Antibodies » Abs to DNA Replication, Repair » Anti -Artemis (DCLRE1C, DNA Cross-link Repair 1C, Protein A-SCID, SNM1 Homolog C, hSNM1C, SNM1-like Protein, ASCID, SCIDA, SNM1C)

Anti -Artemis (DCLRE1C, DNA Cross-link Repair 1C, Protein A-SCID, SNM1 Homolog C, hSNM1C,
SNM1-like Protein, ASCID, SCIDA, SNM1C)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH IF
Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNA-PKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining.
Catalog #A3585-10B
ApplicationsSuitable for use in Immunofluorescence, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to KGLRAPTLKRRLE of human DCLRE1C conjugated to KLH.
SpecificityRecognizes human DCLRE1C.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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