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Specifications

Pure Artocarpus integrifolia (Jacalin) is a lectin composed of four subunits, two of ~10,000D and two of ~16,000D each. This 50,000D glycoprotein appears to bind only O-glycosidically linked oligosaccharides, preferring the structure galactosyl (b-1,3) N-acetylgalactosamine. This structure (the so-called "T-antigen") is the oligosaccharide to which peanut agglutinin binds. Unlike PNA, Jacalin will bind this structure even in a mono- or disialylated form. Jacalin has been used to purify human IgA, since no other human immunoglobulin class binds to Jacalin. The specificity of Jacalin also affords the opportunity to localize or isolate glycoproteins with O-glycosidically linked oligosaccharide side chains.
Catalog #	A3590-11
Activity	<0.5ug/ml will agglutinate neuraminidase treated human erythrocytes.
Carbohydrate Specificity	alpha-Galactose
Inhibitory Carbohydrate	alpha-Galactose
Applications	Suitable for use in IgA-binding and purification. Other applications not tested.
Recommended Dilutions	Optimal dilutions to be determined by researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	N/A
Molecular Weight	52kD
Source	Jackfruit, Breadfruit
Purity	Highly purified.
Concentration	~1mg/ml
Form	Supplied as a liquid in PBS, pH 7.2. Labeled with horseradish peroxidase (HRP).
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	Jacalin; Brazil jackfruit; Breadfruit; AIA