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You are here:Home » Antibodies » Antibodies-Apoptosis » Anti -ARTS (Apoptosis Related Protein in TGF beta Signaling Pathway)

Anti -ARTS (Apoptosis Related Protein in TGF beta Signaling Pathway)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identi ed recently and designated ARTS for apoptosis related protein in TGF-b signaling pathway (1). ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene (1-4) is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-b and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.
Catalog #A3595
Applications Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution Western Blot: 0.5-2ug/ml; Optimal dilutions to be determined by the researcher.
Positive Control Human lung, kidney and spleen tissue lysates
Storage and Stability May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
FormSupplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenRaised against a synthetic peptide (KRFLEDTTDDGE) corresponding to amino acids 3 to 14 of human ARTS (1).
SpecificityRecognizes a band at 32kD.
Important NoteThis product is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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