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You are here:Home » Antibodies » Abs to Transcription Factors » Anti -Ascl1a (Achaete-scute Homolog 1a, Zash-1a, Pituitary-absent Protein, ash, ash1a, asha, pia)

Anti -Ascl1a (Achaete-scute Homolog 1a, Zash-1a, Pituitary-absent Protein, ash, ash1a,
asha, pia)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
Transcriptional regulator. May mediate transcription activation by binding to the E box-containing promoter. Involved in neurogenesis. Required for the development of neurons in the epiphysis, acting partially redundantly with neurog1 and downstream of flh. Involved in maintaining rhombomere boundaries in the hindbrain, probably via up-regulation of delta expression. Also involved in pituitary development; required cell-autonomously in adenohypophyseal cells for endocrine differentiation and for survival of a subset of cells.
Catalog #A3619-80D
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:8000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceZebrafish
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to QCSNKSASKQAKRQR, from Ascl1a, at the internal region of the protein (NP_571294.1).
SpecificityRecognizes Ascl1a. Species sequence homology: Zebrafish.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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