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You are here:Home » Molecular Biology » MB-Chromatin Proteins » ASF1A, aa1-204, Recombinant, Human (Anti-silencing Function 1A, ASF1 Anti-silencing Function 1 Homolog A, CCG1-interacting Factor A, CIA, CGI-98, DKFZp547E2110, hAsf1, hAsf1a, hCIA, Histone Chaperone ASF1A, HSPC146, RP3-329L24.1)

ASF1A, aa1-204, Recombinant, Human (Anti-silencing Function 1A, ASF1 Anti-silencing
Function 1 Homolog A, CCG1-interacting Factor A, CIA, CGI-98, DKFZp547E2110, hAsf1,
hAsf1a, hCIA, Histone Chaperone ASF1A, HSPC146, RP3-329L24.1)

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Specifications

ASF1 anti-silencing function 1 homolog A, also known as ASF1A, belongs to H3/H4 family of histone chaperone proteins. ASF1A protein interacts with histones H3 and H4, and functions together with a chromatin assembly factor during DNA replication and repair. Deletion of ASF1A in yeast and Drosophila confers sensitivity to various DNA damaging agents and inhibitors of DNA replication, increases genomic instability and sister chromatid exchange, and activates the DNA damage checkpoint.
Catalog #A3780-58A
Source Recombinant human ASF1A, fused to His-tag at N-terminus, expressed in E.coli.
Molecular Weight 27kD (240aa)
Endotoxin Level 1.0 EU /1ug of protein (LAL).
AA SequenceMRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMAKV QVNNVVVLDN PSPFYNPFQF EITFECIEDL SEDLEWKIIY VGSAESEEYD QVLDSVLVGP VPAGRHMFVF QADAPNPGLI PDADAVGVTV VLITCTYRGQ EFIRVGYYVN NEYTETELRE NPPVKPDFSK LQRNILASNP RVTRFHINWE DNTEKLEDAE SSNPNLQSLL STDALPSASK GWSTSENSLN VMLESHMDCM
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight27kD
SourceE. coli
Purity90% by SDS-PAGE
Concentration~1.0mg/ml
FormSupplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, 1mM DTT, 10% glycerol.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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