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Anti -ASH1 (MASH1, Helix-loop-helix Transcription Factor, Achaete-scute Complex Homolog-like1, ASCL1)
Anti -ASH1 (MASH1, Helix-loop-helix Transcription Factor, Achaete-scute Complex
Homolog-like1, ASCL1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B |
|
| This protein plays a role in neuronal commitment and differentiantion in most regions of the CNS and of several neuronal lineages in the PNS. It is also essential for the generation of olfactory and autonomic neurons. The unprocessed precursor is 236 amino acids in length and 25.45KDa. ASCL1 contains one basic helix-loop-helix (bHLH) domain. It activates transcription by binding to the Ebox (5'-CANNTG-3') and efficient DNA binding requires dimerisation with other bHLH proteins. It forms a heterodimer with TCF3. | | | Catalog # | A3782-02B | | Applications | Suitable for use in Western Blot and ELISA. Other applications not tested. | | Recommended Dilution | Optimal dilution determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20°C. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 9G315 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophilized powder from PBS, pH 7.2, 150mM sodium chloride. Reconstitute with 100ul sterile ddH2O. | | Purity | Purified by affinity chromatography. | | Immunogen | Partial recombinant protein of human ASCL1 (aa137-237) with a GST tag. | | Specificity | Recognizes human ASH1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Achaete-scute homolog 1, HASH1, GENE NAME: ASCL1, ASH1 |
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