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A3884 Asterric Acid (Dimethylosoic acid, Antibiotic TAN 1415A, Antibiotic WF 12880A) CAS: 577-64-0

Specifications
References
CAS Number
577-64-0
Grade
Highly Purified
Molecular Formula
C17H16O8
Molecular Weight
348.3
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
+4°C
Dimethylosoic acid, Antibiotic TAN 1415A, Antibiotic WF 12880A

A fungal metabolite, asterric acid is isolated from a number of Aspergillus and Penicillium species. It is an inhibitor of vascular endothelial growth factor (VEGF). Asterric acid is an angiogenesis inhibitor acting on VEGF-induced tube formation of human umbilical vein endothelial cells.

Purity: >99% by HPLC
Solubility: Soluble in ethanol, methanol, DMF or DMSO.
Source
Aspergillus terreus
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Fungal metabolites, asterric acid derivatives inhibit vascular endothelial growth factor (VEGF)-induced |tube formation of HUVECs. Lee H.J. et al. J. Antibiot. 2002, 55, 552. |2. Asterric acid, a new endothelin binding inhibitor. Ohashi H. et al. J. Antibiot. 1992, 45, 1684. |3. Studies in the biochemistry of micro-organisms. 115. Metabolites of Penicillium frequentans Westling: |isolation of sulochrin, asterric acid, (+)-bisdechlorogeodin and two new substituted anthraquinones, |questin and questinol. Mahmoodian A. et al. Biochem. J. 1964, 92, 369.
USBio References
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