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Anti -ADMA (Asymmetric Dimethylarginine)
Anti -ADMA (Asymmetric Dimethylarginine)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B IH |
|
| Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells. It is closely related to L-arginine, a conditionally-essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide, a key chemical involved in normal endothelial function and, by extension, cardiovascular health. | | | Catalog # | A3886 | | Applications | Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Optimal dilutions to be determined by the researcher. | | Crossreactivity | Using conjugated ADMA-KLH, antibody specificity was performed with an ELISA test by competition experiments with the following compounds: | | Compound: Cross-reactivity ratio(a) | | ADMA-BSA: 1 | | SDMA-BSA: 1:>100 | | NDMA-BSA: 1:>100 | | L-Arginine-BSA: 1:>5000 | | (a) ADMA-BSA concentration/unconjugated or conjugated amino acids concentration at half displacement BSA=Bovine Serum Albumin | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG1 | | Host | Rabbit | | Concentration | ~1mg/ml (after reconstitution) | | Form | Supplied as a lyophilized powder from 50mM Tris, pH 7.4. Reconstitute with sterile ddH2O to a concentration of 1mg/ml. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | ADMA, conjugated to KLH. | | Specificity | Recognizes ADMA. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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