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You are here:Home » Antibodies » Antibodies-Amino Acids » Anti -ADMA (Asymmetric Dimethylarginine)

Anti -ADMA (Asymmetric Dimethylarginine)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells. It is closely related to L-arginine, a conditionally-essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide, a key chemical involved in normal endothelial function and, by extension, cardiovascular health.
Catalog #A3886
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
CrossreactivityUsing conjugated ADMA-KLH, antibody specificity was performed with an ELISA test by competition experiments with the following compounds:
Compound: Cross-reactivity ratio(a)
SDMA-BSA: 1:>100
NDMA-BSA: 1:>100
L-Arginine-BSA: 1:>5000
(a) ADMA-BSA concentration/unconjugated or conjugated amino acids concentration at half displacement BSA=Bovine Serum Albumin
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
Concentration~1mg/ml (after reconstitution)
FormSupplied as a lyophilized powder from 50mM Tris, pH 7.4. Reconstitute with sterile ddH2O to a concentration of 1mg/ml.
PurityPurified by Protein G affinity chromatography.
ImmunogenADMA, conjugated to KLH.
SpecificityRecognizes ADMA.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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