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You are here:Home » Antibodies » Abs to Autophagy » Anti -ATG4B (Cysteine Protease ATG4B, AUT-like 1 Cysteine Endopeptidase, Autophagin-1, Autophagy-related Cysteine Endopeptidase 1, Autophagy-related Protein 4 Homolog B, hAPG4B, APG4B, AUTL1, KIAA0943)

Anti -ATG4B (Cysteine Protease ATG4B, AUT-like 1 Cysteine Endopeptidase, Autophagin-1,
Autophagy-related Cysteine Endopeptidase 1, Autophagy-related Protein 4 Homolog B, hAPG4B,
APG4B, AUTL1, KIAA0943)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
AG4B is a 393aa cysteine protease consisting of the active catalytic triad site of Cys74, His280 and Asp278 and belonging to the peptidase C54 family. It is required for autophagy, which is essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death and aging. It negatively regulates the localization of LC3 to a membrane compartment by delipidation and mediates murine Atg8L/Apg8L modification during the formation of autophagosomes. APG4B is expressed in skeletal muscle, brain, heart, liver and pancreas.
Catalog #A3935-06M
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1-3ug/ml
Immunohistochemistry (paraffin): 10ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHeLa and RAW cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa350-400 of human APG4B.
SpecificityRecognizes human APG4B. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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