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You are here:Home » Antibodies » Antibodies-Signal Transduction » Anti -Atlastin-3 (ATL3)

Anti -Atlastin-3 (ATL3)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Atlastin is a recently characterized, integral protein GTPase similar to members of the dynamin family of large GTPases. It is primarily localized on the Golgi apparatus and regularly considered to contain two transmembrane domains which result in the exposure of both the N-terminal and C-terminal ends to the cytoplasm. Studies have shown atlastin to bind with spastin in biological pathways, such as microtubule-severing leading to axon outgrowth. Mutations in atlastin expression are causal to childhood onset HSP, a group of conditions in which spastic parapalegia occurs. Atlastin has been found in several tissues throughout the body. The most significant levels of atlastin have been observed in the brain and spinal cord.
Catalog #A3965
Suitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Positive ControlHeLa cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
ConcentrationNot determined.
FormSupplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenLinear peptide corresponding to mouse Atlastin-3 (KLH).
SpecificityRecognizes human Atlastin-3. Species Crossreactivity: mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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