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You are here:Home » Molecular Biology » MB-Hormones, Steroids » Atosiban, Human (ADH, Anti-Diuretic Hormone)

Atosiban, Human (ADH, Anti-Diuretic Hormone)

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Specifications

Atosiban also called ADH (Anti-Diuretic Hormone) has a molecular formula of C43H67N11O12S2, Mpr-Tyr(OEt)-Ile-Thr-Asn-Cys-Pro-Orn-Gly-NH2 having a Mw of 994.2 is the first oxytocin antagonist to be specifically developed for the treatment of preterm labour. Atosiban has a specific mode of action, inhibiting oxytocin-induced uterine contractions lry blocking oxytocin receptors in the uterus. Extensive clinical investigations have shown Atosiban to be at least as effective as current tocolytic agents. In addition, due to its novel and specific mode of action, Atosiban has a markedly improved maternal side effects profile compared with conventional therapies.
Catalog #A4000-44
SolubilityIt is recommended to reconstitute the lyophilized Atosiban in sterile 18M -cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
StabilityStorage and Stability:
Store powder dessicated at -20ºC. Liquid can be stored at 4ºC for 2-7 days, long term at -20ºC. For long term it is recommended to add a carrier protein (0.1% HSA or BSA). Aliquot to prevent repeated freeze-thaw cycles.
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Molecular FormulaC43H67N11O12S2
Molecular Weight994.2
Purity98% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel.
ConcentrationAs reported
FormSupplied as a lyophilized powder without additives.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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