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Anti -ATPase, Ca (Plasma Membrane 1, PMCA1)
Anti -ATPase, Ca (Plasma Membrane 1, PMCA1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IH |
|
| Catalog # | A4000-50A6 | | The Ca(2+)-ATPases are a family of plasma membrane pumps encoded by at least 4 genes | ATP2B1 on chromosome 12q21; ATP2B2; ATP2B3 on Xq28; and ATP2B4 on 1q25. The proteins share 84% aa sequence identity and 76% nucleic acid sequence homology. The function of calcium-transporting ATPase found in different membranes is to lower cytoplasmic Ca(2+) concentration by pumping Ca(2+) to luminal or extracellular spaces. Mutations in a plasma membrane Ca(2+)-ATPase gene cause deafness in deafwaddler mice. | | Application | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 4ug/ml | | Immunohistochemistry (paraffin): 8ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 10K342 | | Host | Mouse | | Source | Human | | Concentration | Not determined. | | Form | Supplied as a lyophilized powder from 1.2% sodium acetate, 2% BSA, 0.01% sodium azide. Reconstitute with PBS. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Human erythrocyte Ca2+-ATPase. | | Specificity | Recognizes human PMCA. Species Crossreactivity: mouse, rat, chicken, rabbit. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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