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You are here:Home » Antibodies » Abs to Disease Markers » Anti -Atrophin 1 (ATN1, DRPLA, Dentatorubral-pallidoluysian Atrophy, NOD)

Anti -Atrophin 1 (ATN1, DRPLA, Dentatorubral-pallidoluysian Atrophy, NOD)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.
Catalog #A4156-15A
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormTris-citrate/phosphate buffer, pH 7 to 8
PurityPurified by immunoaffinity chromatography.
ImmunogenThe epitope recognized maps to a region between residue 1150 and the C-terminus (residue 1190) of human Atrophin 1 using the numbering given in entry NP_001007027.1 (GeneID 1822 ).
SpecificitySpecies Crossreactivity: Human. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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