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You are here:Home » Antibodies » Abs to Ataxin » Anti -ATXN2 (Trinucleotide Repeat-containing Gene 13 Protein, Spinocerebellar Ataxia Type 2 Protein, Ataxin-2, ATX2, SCA2, TNRC13)

Anti -ATXN2 (Trinucleotide Repeat-containing Gene 13 Protein, Spinocerebellar Ataxia Type
2 Protein, Ataxin-2, ATX2, SCA2, TNRC13)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. Defects in this gene are the cause of spinocerebellar ataxia type 2 (SCA2). SCA2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia.
Catalog #A4159-05C
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:2000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-SEREGHSINTR, from ATXN2, at the internal region of the protein (NP_002964.3).
SpecificityRecognizes ATXN2. Species sequence homology: Bovine, canine, human, mouse and porcine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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