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Aureothricin (Propionylpyrrothione, Farcinin)
Aureothricin (Propionylpyrrothione, Farcinin)
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| Aureothricin is an antibiotic first described by Umezawa and co-workers in Japan in 1949. Resurgent interest in this class of microbial metabolites was stimulated by the discovery of their selective antitumor activity. Aureothricin is a more hydrophobic analogue of thiolutin but has received only limited attention. Members of this class, notably, thiolutin, have been shown to potent inhibitors of bacterial and yeast RNA polymerases and inhibitors of mannan and glucan formation in fungi. Studies have shown that thiolutin inhibits tumor cell-induced angiogenesis in vivo. | | | Catalog # | A4174-50 | | DMSO and DMF, partially soluble in methanol and ethanol while poorly soluble in water | | CAS Number | 574-95-8 | | Molecular Formula | C9H10N2O2S2 | | Molecular Weight | 242.32200000000000273 | | Source | Streptomyces sp. | | Purity | > 98% by HPLC | | Form | Yellow orange solid | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Propionylpyrrothione, Farcinin |
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