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You are here:Home » Molecular Biology » MB-Protein Kinases » Aurora Kinase A, Recombinant, Human (SAIK, ARK1, AurA, AURA, Aurora/IPL1-related kinase 1, AURORA2, Aurora-A, Aurora kinase A, Aurora-related kinase 1, Breast tumor-amplified kinase, BTAK, hARK1, MGC34538, Serine/threonine kinase 15, Serine/threonine-prot

Aurora Kinase A, Recombinant, Human (SAIK, ARK1, AurA, AURA, Aurora/IPL1-related kinase 1,
AURORA2, Aurora-A, Aurora kinase A, Aurora-related kinase 1, Breast tumor-amplified
kinase, BTAK, hARK1, MGC34538, Serine/threonine kinase 15, Serine/threonine-prot

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Specifications

Aurora Kinase A is a member of a family of mitotic serine/threonine kinases. It is implicated with important processes during mitosis and meiosis whose proper function is integral for healthy cell proliferation. Aurora kinase A is highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also this protein plays a crucial role in tumorigenesis and is overexpressed in many kinds of cancers.
Catalog #A4189-01Q
SourceRecombinant human Aurora-A fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Molecular Weight47.9kD (423aa).
AA SequenceMGSSHHHHHH SSGLVPRGSH MDRSKENCIS GPVKATAPVG GPKRVLVTQQ FPCQNPLPVN SGQAQRVLCP SNSSQRIPLQ AQKLVSSHKP VQNQKQKQLQ ATSVPHPVSR PLNNTQKSKQ PLPSAPENNP EEELASKQKN EESKKRQWAL EDFEIGRPLG KGKFGNVYLA REKQSKFILA
LKVLFKAQLE KAGVEHQLRR EVEIQSHLRH PNILRLYGYF HDATRVYLIL EYAPLGTVYR ELQKLSKFDE QRTATYITEL ANALSYCHSK RVIHRDIKPE NLLLGSAGEL KIADFGWSVH APSSRRTTLC GTLDYLPPEM IEGRMHDEKV DLWSLGVLCY EFLVGKPPFE ANTYQETYKR ISRVEFTFPD FVTEGARDLI SRLLKHNPSQ RPMLREVLEH PWITANSSKP SNCQNKESAS KQS.
Storage and StabilityFor long-term storage, aliquot and store at -20°C/-70°C. Aliquots are stable for at least 6 months at -20°C/-70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity~95% by SDS-PAGE.
ConcentrationAs reported
FormSupplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.5mM DTT, 100mM NaCl, 0.1mM EDTA, 0.1mM EGTA, 0.1mM PMSF, 20% glycerol.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAurora-A, AIK, ARK1, AURA, BTAK, STK15, STK6


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