Aurora Kinase A, Recombinant, Human (SAIK, ARK1, AurA, AURA, Aurora/IPL1-related kinase 1,
AURORA2, Aurora-A, Aurora kinase A, Aurora-related kinase 1, Breast tumor-amplified
kinase, BTAK, hARK1, MGC34538, Serine/threonine kinase 15, Serine/threonine-prot
Pricing
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| Aurora Kinase A is a member of a family of mitotic serine/threonine kinases. It is implicated with important processes during mitosis and meiosis whose proper function is integral for healthy cell proliferation. Aurora kinase A is highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also this protein plays a crucial role in tumorigenesis and is overexpressed in many kinds of cancers. | | | Catalog # | A4189-01Q | | Source | Recombinant human Aurora-A fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. | | Molecular Weight | 47.9kD (423aa). | | AA Sequence | MGSSHHHHHH SSGLVPRGSH MDRSKENCIS GPVKATAPVG GPKRVLVTQQ FPCQNPLPVN SGQAQRVLCP SNSSQRIPLQ AQKLVSSHKP VQNQKQKQLQ ATSVPHPVSR PLNNTQKSKQ PLPSAPENNP EEELASKQKN EESKKRQWAL EDFEIGRPLG KGKFGNVYLA REKQSKFILA | | LKVLFKAQLE KAGVEHQLRR EVEIQSHLRH PNILRLYGYF HDATRVYLIL EYAPLGTVYR ELQKLSKFDE QRTATYITEL ANALSYCHSK RVIHRDIKPE NLLLGSAGEL KIADFGWSVH APSSRRTTLC GTLDYLPPEM IEGRMHDEKV DLWSLGVLCY EFLVGKPPFE ANTYQETYKR ISRVEFTFPD FVTEGARDLI SRLLKHNPSQ RPMLREVLEH PWITANSSKP SNCQNKESAS KQS. | | Storage and Stability | For long-term storage, aliquot and store at -20°C/-70°C. Aliquots are stable for at least 6 months at -20°C/-70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | | | Source | E. coli | | Purity | ~95% by SDS-PAGE. | | Concentration | As reported | | Form | Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.5mM DTT, 100mM NaCl, 0.1mM EDTA, 0.1mM EGTA, 0.1mM PMSF, 20% glycerol. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Aurora-A, AIK, ARK1, AURA, BTAK, STK15, STK6 |
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Download Specifications for Aurora Kinase A, Recombinant, Human (SAIK, ARK1, AurA, AURA, Aurora/IPL1-related kinase 1, AURORA2, Aurora-A, Aurora kinase A, Aurora-related kinase 1, Breast tumor-amplified kinase, BTAK, hARK1, MGC34538, Serine/threonine kinase 15, Serine/threonine-prot |
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