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You are here:Home » Antibodies » Abs to Protein Kinase Substrates » Anti -AURKA, phosphorylated (Thr288) (Serine/Threonine-protein Kinase 6, Aurora Kinase A, Aurora/IPL1-related Kinase 1, ARK-1, Aurora-related Kinase 1, hARK1, Breast Tumor-amplified Kinase, Serine/Threonine-protein Kinase 15, Serine/Threonine-protein Kinase Aur

Anti -AURKA, phosphorylated (Thr288) (Serine/Threonine-protein Kinase 6, Aurora Kinase A,
Aurora/IPL1-related Kinase 1, ARK-1, Aurora-related Kinase 1, hARK1, Breast
Tumor-amplified Kinase, Serine/Threonine-protein Kinase 15, Serine/Threonine-protein
Kinase Aur

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.
Catalog #A4189-06H
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry:1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic phosphopeptide corresponding to human AURKA around the phosphorylation site of threonine 288 (R-T-TP-L-M).
SpecificityRecognizes human AURKA when phosphorylated at Thr288. Species Cross-Reactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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