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You are here:Home » Antibodies » Abs to Apoptosis, Caspase » Anti -Aven (Apoptosis Caspase Activation Inhibitor, Cell Death Regulator Aven, PDCD12)

Anti -Aven (Apoptosis Caspase Activation Inhibitor, Cell Death Regulator Aven, PDCD12)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
PDCD12 (Programmed cell death 12), also referred to as AVEN, represents a new class of cell death regulator. PDCD12 is a conserved intracellular membrane protein that blocks apoptosis impeded by Apaf-1 mediated caspase activation. Bcl-2 and BAD also interact with PDCD12 to prevent apoptosis. It is expressed in a wide variety of normal tissues including heart, skeletal muscle, kidney, liver, testis, and diseases such as cancer
Applications:
Suitable for use in ELISA and Western Blot Other applications not tested.
Catalog #A4445-11L
Recommended DilutionWestern Blot: 1:1000-3000
Optimal dilutions to be determined by the researcher.
HybridomaHybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PDCD12 protein.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No9C85
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant human PDCD12 (254-362aa) purified from E. coli
SpecificityRecognizes human PDCD12 (Programmed cell death 12, AVEN).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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