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You are here:Home » Antibodies » Abs to Receptors, Tyrosine Kinase » Anti -AXL (Tyrosine-protein Kinase Receptor UFO, AXL Oncogene, UFO)

Anti -AXL (Tyrosine-protein Kinase Receptor UFO, AXL Oncogene, UFO)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites E B IH IF
Axl, an Axl type tyrosine kinase, is characterized by an extracellular domain resembling cell adhesion molecules and an intracellular conserved tyrosine kinase domain. Axl has been reported to induce cell proliferation and transformation, and is important in the vasculature functions. Expression of AXL has been seen in many cancers, including those of the lung, breast, stomach, thyroid, liver, and more. Two protein isoforms of Axl have been documented. It has been suggested that Gas6/Axl signaling may impact on the response of blood vessels to injury, thereby contributing to the development of atherosclerosis and/or restenosis.
Catalog #A4775-12
ApplicationsSuitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:2000
Immunofluorescence: 1:200-1:1000
Immunohistochemistry (Formalin fixed paraffin embedded): 1:200
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No7E10
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid, 0.03% sodium azide.
PurityAscites
ImmunogenRecombinant corresponding to extracellular fragment of human AXL fused with hIgGFc tag expressed in HEK293 cell line.
SpecificityRecognizes human AXL.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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