Anti -Axl, phosphorylated (Tyr779) (AXL Oncogene, AXL Receptor Tyrosine Kinase, AXL
Transforming Gene, AXL Transforming Sequence/gene, Adhesion-related Kinase, Ark, Oncogene
AXL, Tyrosine Protein Kinase Receptor, UFO, TYR07)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH IC |
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| Axl (also known as ARK, UFO and TYR07) is a receptor tyrosine kinase that contains extracellular regions composed of two IgG-related domains linked to two fibronectin type III repeats. Gas6, a ligand for Axl, induces Axl phosphorylation on multiple tyrosine residues. Phosphorylation of Axl at Tyr779 is associated with the activation of PI 3-kinase. | | | Catalog # | A4776-10 | | Applications | Suitable for use in Western Blot, Immunocytochemistry and Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Western Blot: 1ug/ml detects Axl in Wl38 human lung cell line conditioned media-treated A172 human glioblastoma cell line. | | Immunocytochemistry: 5-15ug/ml detects Axl in immersion fixed A172 human glioblastoma cell line with and without pervanadate co-staining with total Axl. | | Immunohistochemistry: 5-15ug/ml detects Axl in immersion fixed paraffin embedded sections of human stomach. | | Optimal dilution to be determined by researcher. | | Recommended Secondary Antibodies | I1904-39: IgG, X-Adsorbed (HRP) Pab Gt x Rb | | I1904-40A: IgG, H&L, X-Adsorbed (HRP) Pab Gt x Rb | | I1904-46Q: IgG, H&L (HRP) Pab Gt x Rb | | | | Storage and Stability: | | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.2mg/ml (after reconstitution) | | Form | Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 500ul sterile PBS. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Synthetic phosphopeptide corresponding to human Axl Tyr779 site. | | Specificity | Recognizes endogenous human Axl, phosphorylated at Tyr779. Species Crossreactivity: mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Axl, phosphorylated (Tyr779) (AXL Oncogene, AXL Receptor Tyrosine Kinase, AXL Transforming Gene, AXL Transforming Sequence/gene, Adhesion-related Kinase, Ark, Oncogene AXL, Tyrosine Protein Kinase Receptor, UFO, TYR07) |
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