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You are here:Home » Antibodies » Abs to Apoptosis » Anti -BACE1 (Beta-site Amyloid Precursor Protein Cleaving Enzyme 1, Beta-site APP Cleaving Enzyme 1, BACE, Aspartyl Protease 2, Asp 2, ASP2, Beta-secretase 1, FLJ90568, HSPC104, KIAA1149, Memapsin-2, Membrane-associated Aspartic Protease 2)

Anti -BACE1 (Beta-site Amyloid Precursor Protein Cleaving Enzyme 1, Beta-site APP Cleaving
Enzyme 1, BACE, Aspartyl Protease 2, Asp 2, ASP2, Beta-secretase 1, FLJ90568, HSPC104,
KIAA1149, Memapsin-2, Membrane-associated Aspartic Protease 2)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
Bace 1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Catalog #B0002-88H
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: 5ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman porstate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.7, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to N-terminus of human BACE1 (KLH).
SpecificityRecognizes human BACE1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesBeta-site APP-cleaving Enzyme 1, EC=3.4.23.46


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