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You are here:Home » Antibodies » Abs to Apoptosis » Anti -BACE1, NT (Beta-secretase 1, Beta-site APP Cleaving Enzyme 1, Beta-site Amyloid Precursor Protein Cleaving Enzyme 1, Aspartyl Protease 2, Asp 2, ASP2, Membrane-associated Aspartic Protease 2, Memapsin-2, BACE1, BACE, KIAA1149)

Anti -BACE1, NT (Beta-secretase 1, Beta-site APP Cleaving Enzyme 1, Beta-site Amyloid
Precursor Protein Cleaving Enzyme 1, Aspartyl Protease 2, Asp 2, ASP2, Membrane-associated
Aspartic Protease 2, Memapsin-2, BACE1, BACE, KIAA1149)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B IH
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
Catalog #B0002-90H3
ApplicationsSuitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenSynthetic peptide selected from the N-terminal region of human BACE1 (KLH).
SpecificityRecognizes human BACE1. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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