Anti -BACE2, ID (Beta-secretase 2, Beta-site Amyloid Precursor Protein Cleaving Enzyme 2,
Beta-site APP Cleaving Enzyme 2, Aspartyl Protease 1, Asp 1, ASP1, Membrane-associated
Aspartic Protease 1, Memapsin-1, Aspartic-like Protease 56kD, Down Region Aspartic P
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B FC |
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| Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by BACE2. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. | | | Catalog # | B0002-92E9 | | Applications | Suitable for use in ELISA, Western Blot, and Flow Cytometry. Other applications not tested. | | Recommended Dilution | Western Blot: 1:100-1:500 | | ELISA: 1:1,000 | | Flow Cytometry: 1:10-1:50 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.25mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide selected from the center region of human BACE2 (KLH). | | Specificity | Recognizes human BACE2. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -BACE2, ID (Beta-secretase 2, Beta-site Amyloid Precursor Protein Cleaving Enzyme 2, Beta-site APP Cleaving Enzyme 2, Aspartyl Protease 1, Asp 1, ASP1, Membrane-associated Aspartic Protease 1, Memapsin-1, Aspartic-like Protease 56kD, Down Region Aspartic P |
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