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Anti -BACE2, Asp1 (NT) (Beta-site APP Cleaving Enzyme, Aspartyl Protease 2, DRAP, Down Region Aspartic Protease, Memapsin)
Anti -BACE2, Asp1 (NT) (Beta-site APP Cleaving Enzyme, Aspartyl Protease 2, DRAP, Down
Region Aspartic Protease, Memapsin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| Catalog # | B0003-01A | | Applications | Western Blot | | Optimal working dilutions to be determined by researcher. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~5mg/ml | | Form | Supplied as a liquid in PBS with 0.02% sodium azide. | | Purity | Purified IgG was prepared from whole serum by affinity chromatography. | | Immunogen | Synthetic peptide corresponding to amino acids 44-59 of human BACE2.. | | Specificity | Recognizes an epitope within the N-terminal region of BACE2, a homologue of the beta-site APP cleaving enzyme (BACE). BACE2 has been reported to cleave the beta-amyloid precursor protein (APP) at the beta-site, producing amyloid-beta protein (ABeta). Accumulation of ABeta plaques in the cerebral cortex play an important role in the pathogenesis of Alzheimer's disease, particularly in individuals bearing the Flemish mutation. Species crossreactivity Mouse, rat | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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