You are here:Home
»
Antibodies
»
Abs to Chromatin Proteins
»
Anti -BAF57 (BRG1 Associated Factor 57, Mammalin Chromatin Remodeling Complex, SMARCE1, SWI/SNF-related Matrix-associated Actin-dependent Regulator of Chromatin e1)
Anti -BAF57 (BRG1 Associated Factor 57, Mammalin Chromatin Remodeling Complex, SMARCE1,
SWI/SNF-related Matrix-associated Actin-dependent Regulator of Chromatin e1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| The SWI/SNF complex in S. cerevisiae and Drosophila is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. The complex contains an ATP-dependent nucleosome disruption activity that can lead to enhanced binding of transcription factors. The BRG1/brm associated factors, or BAF, complex in mammals is functionally related to SWI/SNF and consists of 9 to 12 subunits, some of which are homologous to SWI/SNF. A 57kD BAF subunit, BAF57, is present in higher eukaryotes, but not in yeast. | | | Catalog # | B0003-63P | | Cellular Localization | Nuclear | | Positive Control | HeLa or Jurkat whole cell lysate. | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:16,000. | | Western Blot: 1ug/ml. ~ 37kD band in Hela and Human Brain lysates. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | | | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in TBS, pH 7.2, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide: PPTDPIPEDEKKE, representing the C-terminus of the human protein (residues 399-411), according to NP_003070. | | Specificity | Species Crossreactivity: Crossreacts with Human. Expected to crossreact with Mouse (99% identity with immunogen) due to sequence homology. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
