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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -BAFF (B cell Activating Factor, B Lymphocyte Stimulator, BLYS, CD257, CD257 Antigen, Delta BAFF, Dendritic Cell-derived TNF-like Molecule, DTL Precursor, TNF- and APOL-related Leukocyte Expressed Ligand 1, TALL 1, TALL1, TALL-1, TNF Homolog That Activates

Anti -BAFF (B cell Activating Factor, B Lymphocyte Stimulator, BLYS, CD257, CD257 Antigen,
Delta BAFF, Dendritic Cell-derived TNF-like Molecule, DTL Precursor, TNF- and APOL-related
Leukocyte Expressed Ligand 1, TALL 1, TALL1, TALL-1, TNF Homolog That Activates

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
CD257 (otherwise known as BAFF/BLyS) is a 285 amino acid type II transmembrane protein and member of the tumor necrosis factor (TNF) superfamily of ligands, which acts as a B and T cell stimulator and plays a role in the development of autoimmune diseases such as systemic lupus erythematosus.
Catalog #B0003-66D
CD257 is expressed by monocytes, macrophages, T cells and dendritic cells and acts through binding to CD267 (TACI), CD269 (BCMA) and CD268 (BAFFR) receptors, the latter interaction playing a critical role in the activation, survival, differentiation and proliferation of B cells.
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionsELISA: 5-6ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No10B1151
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a lyophilized powder from PBS, pH 7.2. No preservative added. Reconstitute with 500ul sterile ddH2O.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant full-length mature human CD257 expressed in E. coli.
SpecificityRecognizes human CD257. Antibody is not cross-adsorbed and may react with homologous proteins from related species.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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