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You are here:Home » Growth Factors, Cytokines » Growth Factors-BAFF » BAFF, Recombinant, Human (B cell Activating Factor, B Lymphocyte Stimulator, BLYS, CD257, CD257 Antigen, Delta BAFF, Dendritic Cell-derived TNF-like Molecule, DTL Precursor, TNF- and APOL-related Leukocyte Expressed Ligand 1, TALL 1, TALL1, TALL-1, TNF Ho

BAFF, Recombinant, Human (B cell Activating Factor, B Lymphocyte Stimulator, BLYS, CD257,
CD257 Antigen, Delta BAFF, Dendritic Cell-derived TNF-like Molecule, DTL Precursor, TNF-
and APOL-related Leukocyte Expressed Ligand 1, TALL 1, TALL1, TALL-1, TNF Ho

Pricing

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Specifications

CD257 (BAFF) is a type II transmembrane protein and member of the tumor necrosis factor (TNF) superfamily of ligands, which acts as a B and T cell stimulator and is involved in autoimmune disease. CD257 acts through binding to CD267 (TACI), CD269 (BCMA) and CD268 (BAFFR) receptors, the latter interaction playing a critical role in the activation, survival, differentiation and proliferation of B cells.
Source:
Recombinant human CD257 expressed in E.coli.
Catalog #B0003-66E
ActivityDetermined by a mouse splenocyte survival assay. The expected ED50 for this effect is 0.5-2.0ug/ml.
ApplicationsSuitable for use in Functional Assays. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight17.0kD
SourceE.coli.
Purity~95% by SDS PAGE and HPLC analysis. Endotoxin: 1EU/ug.
FormSupplied as a lyophilized powder. Reconstitute with 200ul sterile dH2O .
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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