Anti -BAFF Receptor (BAFFR, BAFF-R, BAFF Receptor, B Cell-Activating Factor Receptor, BLyS
Receptor 3, BR3, CD268, CD268 antigen, MGC138235, Tumor Necrosis Factor Receptor
Superfamily Member 13C, TNFRSF13C)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
IH FC |
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| B cell-activating factor receptor (BAFF-R) is a 19kD type III membrane protein. It belongs to TNFR superfamily, also known as TNFRSF member 13C (TNFRSF13C), BAFF receptor 3 (BR3), or CD268. BAFF-R is expressed on mature B cells, B cell lymphoma, and T cell subset. BAFF-R is the major receptor for BAFF/BLys (or TALL-1, THANK) which binds to TACI and BCMA as well. The interaction of BAFF with BAFF-R promotes NF-ê B activation and plays predominant roles in B-cell maturation and survival as well as costimulates T cell activation and proliferation. TRAF3 is a BAFF-R intracellularly associated protein, which negatively regulates BAFF-R-mediated NF-ê B activation. | | | Catalog # | B0003-68C | | Applications | Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | | | Immunohistochemistry: Frozen and paraffin sections | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 6D146 (11C1) | | Host | Mouse | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, 0.02% sodium azide before the addition of glycerol to 40%. | | Purity | Purified by Protein G affinity chromatography. >95% SDS-PAGE. | | Immunogen | Mouse B cell lymphoma L1.2 cells expressing human BAFF-R. | | Specificity | Recognizes endogenous human BAFF-R. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -BAFF Receptor (BAFFR, BAFF-R, BAFF Receptor, B Cell-Activating Factor Receptor, BLyS Receptor 3, BR3, CD268, CD268 antigen, MGC138235, Tumor Necrosis Factor Receptor Superfamily Member 13C, TNFRSF13C) |
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