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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -BAFF Receptor (BAFFR, BAFF-R, BAFF Receptor, B Cell-Activating Factor Receptor, BLyS Receptor 3, BR3, CD268, CD268 antigen, MGC138235, Tumor Necrosis Factor Receptor Superfamily Member 13C, TNFRSF13C)

Anti -BAFF Receptor (BAFFR, BAFF-R, BAFF Receptor, B Cell-Activating Factor Receptor, BLyS
Receptor 3, BR3, CD268, CD268 antigen, MGC138235, Tumor Necrosis Factor Receptor
Superfamily Member 13C, TNFRSF13C)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IH FC
B cell-activating factor receptor (BAFF-R) is a 19kD type III membrane protein. It belongs to TNFR superfamily, also known as TNFRSF member 13C (TNFRSF13C), BAFF receptor 3 (BR3), or CD268. BAFF-R is expressed on mature B cells, B cell lymphoma, and T cell subset. BAFF-R is the major receptor for BAFF/BLys (or TALL-1, THANK) which binds to TACI and BCMA as well. The interaction of BAFF with BAFF-R promotes NF-ê B activation and plays predominant roles in B-cell maturation and survival as well as costimulates T cell activation and proliferation. TRAF3 is a BAFF-R intracellularly associated protein, which negatively regulates BAFF-R-mediated NF-ê B activation.
Catalog #B0003-68C
ApplicationsSuitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested.
Recommended Dilutions
Immunohistochemistry: Frozen and paraffin sections
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No6D146 (11C1)
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide before the addition of glycerol to 40%.
PurityPurified by Protein G affinity chromatography. >95% SDS-PAGE.
ImmunogenMouse B cell lymphoma L1.2 cells expressing human BAFF-R.
SpecificityRecognizes endogenous human BAFF-R.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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