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Bafilomycin A1
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| Bafilomycin A1 is a member of a potent family of macrocyclic lactones with a broad spectrum of biological activity including activity against bacteria, yeast, fungi, nematodes, insects and antitumor cell lines. Bafilomycin A1 is an inhibitor of vacuolar-type ATPase. | | | Catalog # | B0003-70A | | Related to | Bafilomycin B1, Bafilomycin C1, Concanamycin A | | Solubility | Freely soluble in DMSO; may react with methanol or ethanol, so these solvents are not recommended for stock solutions; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-10uM; buffers, serum, or other additives may increase or decrease the aqueous solubility. | | Melting Point | 151.5-152ºC | | Elemental Analysis | Calculated: | | C: 67.49% | | H: 9.39% | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Protect from light. | | CAS Number | 88899-55-2 | | Molecular Formula | C35H58O9 | | Molecular Weight | 622.8 | | Source | Streptomyces sp. MST-AS5338 | | Purity | ~90% by HPLC | | Form | Supplied as a white solid. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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