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You are here:Home » Biochemicals » Biochem-Antibiotics » Bafilomycin A1

Bafilomycin A1


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Bafilomycin A1 is a member of a potent family of macrocyclic lactones with a broad spectrum of biological activity including activity against bacteria, yeast, fungi, nematodes, insects and antitumor cell lines. Bafilomycin A1 is an inhibitor of vacuolar-type ATPase.
Catalog #B0003-70A
Related to Bafilomycin B1, Bafilomycin C1, Concanamycin A
SolubilityFreely soluble in DMSO; may react with methanol or ethanol, so these solvents are not recommended for stock solutions; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-10uM; buffers, serum, or other additives may increase or decrease the aqueous solubility.
Melting Point151.5-152ºC
Elemental AnalysisCalculated:
C: 67.49%
H: 9.39%
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Protect from light.
CAS Number88899-55-2
Molecular FormulaC35H58O9
Molecular Weight622.8
SourceStreptomyces sp. MST-AS5338
Purity~90% by HPLC
FormSupplied as a white solid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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