Bafilomycin B1 CAS 88899-56-3

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B0003-71 Bafilomycin B1 (Setamycin) CAS: 88899-56-3

Specifications

References

CAS Number

88899-56-3

Grade

Highly Purified

Molecular Formula

C44H65NO13

Molecular Weight

816

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

+4°C

Setamycin

Bafilomycin B1 shares the same mode of action and activity as its more accessible A1 analogue Bafilomycin B1 is broadly active against bacteria, fungi, insects, nematodes and protozoans. Bafilomycin B1 has attracted interest as a potential antiosteoporotic agent in treating bone lytic diseases.

Purity: >95% by HPLC

Solubility: Soluble in ethanol, methanol, DMF or DMSO. NOTE: forms methyl ketal on long term storage in methanol

Related to: Bafilomycin A1, Bafilomycin C1, Concanamycin A

Source

Streptomyces sp.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

References

1. Structure and function of V-ATPases in osteoclasts: potential therapeutic targets for the treatment of |osteolysis. Xu J. et al. J. Histol. Histopathol. 2007, 22, 443. |2. Bafilolides, Potent Inhibitors of the Motility and Development of the Free-Living Stages of Parasitic |Nematodes. Lacey E. et al. Int. J. Parasitol. 1995, 25, 349.