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You are here:Home » Biochemicals » Biochem-Antibiotics » Bafilomycin D (Tubaymycin, Antibiotic 3D5)

Bafilomycin D (Tubaymycin, Antibiotic 3D5)

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Specifications

Bafilomycin D shares the same mode of action as bafilomycin A1 which has been the analog of choice in cell biology studies of the role of ATPase. Bafilomycin D contains the ring opened side chain and is a much more stable analog of bafilomycin A1. In-house data demonstrate that bafilomycin D is also a much more selective inhibitor of mammalian cells than bafilomycin A which exhibits a broad profile against tumor cells, fungi and nematodes. Limited availability has restricted a more in depth investigation of this metabolite.
Catalog #B0003-73
SourceBafilomycin D
Molecular Weight~604.8
SolubilitySoluble in ethanol, methanol, DMF or DMSO.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ethanol, methanol, DMF or DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number98813-13-9
Molecular FormulaC35H56O8
Molecular Weight604.8
SourceStreptomyces sp. MST-AS5343
Purity95% by HPLC
FormSupplied as a white solid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Alternate namesTubaymycin, Antibiotic 3D5


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