BAG1, aa1-230, Recombinant, Human (BAG Family Molecular Chaperone Regulator 1, BAG-1, BCL-2 Associated Athanogene 1, BCL-2-associated Athanogene 1, BCL2-associated Athanogene, HAP, RAP46)
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| BCL2-associated athanogene, also known as BAG1, is a member of the Bcl-2 family of proteins that play varied stimulatory or inhibitory roles in the regulation of programmed cell death. This functions in conjunction with Bcl-2 to inhibit apoptosis. Also, BAG1 has been implicated in age related neurodegenerative diseases as Alzheimer's. It is localized to the cytosol, nucleus or both. Recombinant human BAG1 was expressed in E. coli. | | | Catalog # | B0003-82H | | Source | Recombinant corresponding to aa1-230 of human BAG1 expressed in E. coli. | | AA Sequence | MNRSQEVTRD EESTRSEEVT REEMAAAGLT VTVTHSNEKH DLHVTSQQGS SEPVVQDLAQ VVEEVIGVPQ SFQKLIFKGK SLKEMETPLS ALGIQDGCRV MLIGKKNSPQ EEVELKKLKH LEKSVEKIAD QLEELNKELT GIQQGFLPKD LQAEALCKLD RRVKATIEQF MKILEEIDTL ILPENFKDSR LKRKGLVKKV QAFLAECDTV EQNICQETER LQSTNFALAE | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | Molecular Weight | 25.9kD | | Source | E. coli | | Purity | ~ 90% (SDS-PAGE). Purified by using conventional chromatography techniques. | | Concentration | As reported | | Form | Supplied as a liquid in 20mM Tris HCl, pH 7.5, 100mM NaCl, 10% glycerol. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | BCL-2 Binding Athanogene 1, Glucocorticoid Receptor-associated Protein RAP46 |
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