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You are here:Home » Antibodies » Abs to Neuroscience » Anti -BAIAP2 (Brain-specific Angiogenesis Inhibitor 1-associated Protein 2, BAI-associated Protein 2, BAI1-associated Protein 2, Protein BAP2, Fas Ligand-associated Factor 3, FLAF3, Insulin Receptor Substrate p53/p58, IRS-58, IRSp53/58, IRSp53, Insulin Receptor

Anti -BAIAP2 (Brain-specific Angiogenesis Inhibitor 1-associated Protein 2, BAI-associated
Protein 2, BAI1-associated Protein 2, Protein BAP2, Fas Ligand-associated Factor 3, FLAF3,
Insulin Receptor Substrate p53/p58, IRS-58, IRSp53/58, IRSp53, Insulin Receptor

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.
Catalog #B0041-19F
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: >1:64,000
Western Blot: 1-3ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman brain
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to SGSGTLVSTV, from the C-terminus of the protein sequence according to NP_059344.
SpecificityRecognizes human BAIAP2. Species sequence homology: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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