Anti -Band 3, phosphorylated (Tyr359) (Band 3 Anion Exchange Protein, Band-3 Anion Transport Protein, BND3, Anion Exchange Protein 1, Anion Exchanger 1, AE1, Erythrocyte Membrane Protein Band 3 Diego Blood Group, CD233, CD233 Antigen, DI, Erythrocyte Membrane P
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
Supernatant |
B |
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| The AE1 (anion exchanger, band 3) protein is expressed in erythrocytes and in the A-type intercalated cells of the kidney distal collecting tubule. In both cell types it mediates the electroneutral transport of chloride and bicarbonate ions across the lipid bilayer, and, in erythrocytes (1). AE1 is phosphorylated on Tyr359 and Tyr404 by Lyn in erythrocytes. Phosphorylation of these residues is necessary for correct localization and recycling of kidney AE1 to the basolateral membrane (2). | | | | | | Applications: | | | Suitable for use in Western Blot. Other applications not tested. | | | Catalog # | B0072-05 | | Recommended Dilution | Western Blot: 1:50,000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 9H297 | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% glycerol, 0.01% sodium azide and 0.05% BSA. | | Purity | Supernatant | | Immunogen | A phospho-specific peptide corresponding to residues surrounding tyrosine 359 of human AE1. | | Specificity | Recognizes human AE1 when phosphorylated at Tyr359. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Band 3, phosphorylated (Tyr359) (Band 3 Anion Exchange Protein, Band-3 Anion Transport Protein, BND3, Anion Exchange Protein 1, Anion Exchanger 1, AE1, Erythrocyte Membrane Protein Band 3 Diego Blood Group, CD233, CD233 Antigen, DI, Erythrocyte Membrane P |
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