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Anti -BARD1 (BRCA1 Associated Ring Domain 1)
Anti -BARD1 (BRCA1 Associated Ring Domain 1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP |
|
| BARD1 possesses an N-terminal RING motif and the C-terminal BRCT domain. As the name suggests, this protein is the major cellular binding protein of BRCA1. BARD1 is thought to play a key role in regulating BRCA1 stability, localisation and function. BARD1 is also reported to function as a tumor suppressor, since mutations in this protein have been implicated in a number of breast and ovarian cancers. | | | Catalog # | B0085 | | Applications | Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Western Blot: 1:500-1:5000 | | Immunoprecipitation: 1-4ug/0.1mg lysate. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris-citrate/phosphate, pH 7-8, 0.1% sodium azide, before the addition of glycerol to 40%. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide, which represented a portion of human BRCA1 associated Ring domain 1 encoded within exon 4. | | Specificity | Recognizes human BARD1 (BRCA1 Associated Ring Domain 1). Species Sequence Homology | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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