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You are here:Home » Antibodies » Abs to Cancer Markers » Anti -BARD1 (BRCA1 Associated Ring Domain 1)

Anti -BARD1 (BRCA1 Associated Ring Domain 1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
BARD1 possesses an N-terminal RING motif and the C-terminal BRCT domain. As the name suggests, this protein is the major cellular binding protein of BRCA1. BARD1 is thought to play a key role in regulating BRCA1 stability, localisation and function. BARD1 is also reported to function as a tumor suppressor, since mutations in this protein have been implicated in a number of breast and ovarian cancers.
Catalog #B0085-01J
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:2500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, 1% BSA, 0.02% thimerosal, 30% glycerol.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide corresponding to human BARD1.
SpecificityRecognizes human BARD1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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