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You are here:Home » Antibodies » Abs to Proteins » Anti -BANF1, CT (Barrier-to-autointegration Factor, Breakpoint Cluster Region Protein 1, BAF, BCRG1)

Anti -BANF1, CT (Barrier-to-autointegration Factor, Breakpoint Cluster Region Protein 1,
BAF, BCRG1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B IF
Barrier-to-autointegration factor 1 (BANF1) is a conserved chromatin protein that non-specifically binds double- stranded DNA. BANF1 also interacts with a family of nuclear proteins that include LAP2, emerin, and MAN1. It is also a host cell component of retroviral pre-integration complexes (PICs), including that of HIV. BANF1 will bind to p55 Gag (the structural precursor of HIV-1 virions) as well as its cleaved product matrix. In addition to being a host cell component of the PIC, it is thought that BANF1 is also present at low levels in incoming virions, and thus might contribute to the assembly or activity of HIV-1 PICs through direct binding to matrix as well as DNA. Despite its predicted molecular weight, BANF1 often migrates at a higher size in SDS-PAGE.
Catalog #B0094-28F
ApplicationsSuitable for use in ELISA, Western Blot and Immunofluorescence. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman kidney tissue lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified
ImmunogenSynthetic peptide corresponding to 15aa from near the C-terminus of human BANF1.
SpecificityRecognizes human BANF1. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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