| ADP-ribosylation factor (ARF)-like proteins (ARLS) comprise a functionally distinConnecticut roup of the ARF family of RAS-related GTPases. This protein binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTpase-activating protein activity. |
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| Catalog # | B0094-36 |
| Applications | Suitable for use in ELISA, Immunohistochemistry, Immunocytochemistry and Western Blot. Other applications not tested. |
| Recommended Dilution | Western Blot: 1:500 |
| Immunohistochemistry: 1:200 |
| Immunocytochemistry: 1:200 |
| Optimal dilutions to be determined by the researcher. |
| Recommended Secondary Antibodies | I1906 IgY, Chicken Pab Rb x Ch |
| I1906-10 IgY, Chicken-HRP Rb x Ch |
| I1906-12 IgY, Chicken-FITC Rb x Ch |
| I1906-14 IgY, Chicken-AP Rb x Ch |
| Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
| CAS Number | n/a |
| Clone Type | Polyclonal |
| Isotype | IgY |
| Host | Chicken |
| Source | Human |
| Concentration | ~1mg/ml |
| Form | Supplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free. |
| Purity | Purified by immunoaffinity chromatography. |
| Immunogen | Synthetic peptide corresponding to aa1-163 |
| Specificity | Recognizes human BART1. |
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| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
