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You are here:Home » Antibodies » Abs to Cancer Markers » Anti -BCAS1 (Breast Carcinoma Amplified Sequence 1)

Anti -BCAS1 (Breast Carcinoma Amplified Sequence 1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
A novel gene, BCAS1 is implicated in breast cancer development. Breast tumor lines that harbor amplification of the cancer-related amplicon 20q13.2 display high levels of the BCAS1 protein compared to normal human fibroblasts or a breast cancer line that does not overexpress the BCAS1 mRNA.
Catalog #B0395-40
ApplicationsSuitable for use in Western Blotting. Other applications not tested.
Recommended DilutionWestern Blotting: 1:500-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add glycerol (40-50%) aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenResidues 532-550 [DTNSLQNGDKLQKRPEKRQ] of human NABC1.
SpecificityReacts with residues 532-550 [DTNSLQNGDKLQKRPEKRQ] of human BCAS1. BCAS1 is a 60kD protein; however it forms dimers, which are readily detectable in MCF-7 cells. Reactivity to other species unknown.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAIBC1, Amplified and overexpressed in breast cancer, Novel amplified in breast cancer 1, NABC1


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