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You are here:Home » Antibodies » Abs to Cancer Markers » Anti -BCAS2 (Breast Carcinoma Amplified Sequence 2, Spliceosome Associated Protein)

Anti -BCAS2 (Breast Carcinoma Amplified Sequence 2, Spliceosome Associated Protein)

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Specifications

Clone Host Grade Applications
Polyclonal Chicken Affinity Purified E B
Using an 8-way (i.e., 8 cell lines) differential display analysis, followed by screening a fetal brain cDNA library, Nagasaki et al. (1999) isolated a cDNA encoding BCAS2, which they termed DAM1 (DNA amplified in mammary carcinoma-1). The deduced 225-amino acid protein contains a central potential N-glycosylation site and multiple N-terminal potential phosphorylation sites. Northern and Southern blot analyses revealed expression of a 1.5-kb transcript at various levels in multiple breast cancer cell lines, with greatest amplification in BT-20 and MCF-7 cells. BCAS2 was ubiquitously expressed in normal tissues.
Catalog #B0395-51
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:2000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgY
HostChicken
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa1-225
SpecificityRecognizes human BCAS2. Species Crossreactivity: Mouse, rat, and Xenopus.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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